The 2025 Toyota Highlander wins on efficiency: 25 vs 21 MPG combined in the tested configurations. The EPA estimates the 2025 Toyota Highlander costs about $500 less per year to fuel. Both earn the same NHTSA overall safety rating (5 of 5 stars).
| 2025 Toyota Highlander | 2025 Honda Pilot | |
|---|---|---|
| Body style | SUV | SUV |
| Engine | 4-cyl 2.4L SIDI & PFI; with Stop-Start | 6-cyl 3.5L SIDI |
| Drivetrain | Front-Wheel Drive | All-Wheel Drive |
| Fuel | Regular Gasoline | Regular Gasoline |
| City MPG | 22 | 19 |
| Highway MPG | 29 | 25 |
| Combined MPG | 25 | 21 |
| EPA est. annual fuel cost | $2,600 | $3,100 |
| NHTSA overall safety | ★★★★★ (5/5) | ★★★★★ (5/5) |
| NHTSA front crash | 4/5 | 4/5 |
| NHTSA side crash | 5/5 | 5/5 |
| NHTSA rollover | 4/5 | 4/5 |
| Tested configuration | Auto (S8), 4 cyl, 2.4 L, Turbo, SIDI & PFI; with Stop-Start | Auto (S10), 6 cyl, 3.5 L |
Data: official EPA fuel economy (fueleconomy.gov) and NHTSA crash-test ratings, pulled September 2026 for the configurations shown. Different trims, drivetrains and model years will change these numbers.